Publications – Sorted by Date

2026

Abele M, Virgone C, Kuhlen M, Irtan S, Reguerre Y, Krawczyk M, et al. Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations. Pediatric Blood & Cancer. n/a(n/a):e70190. doi:10.1002/1545-5017.70190

Ali RH, Hamdy D, Nasr A, Khalifa N, Agaimy A. YAP1::TFE3–rearranged inflammatory spindle cell PEComa of the anterior mediastinum in a 5-year-old child: first pediatric case. Virchows Arch. 2026 Mar 6. doi:10.1007/s00428-026-04470-w

Arega G, Hamza AK, Adane L, Tilahun M, Gemechu FA, Gobez AM. Pediatric parotid mucoepidermoid carcinoma: a case report. Discov Onc. 2026 May 7;17(1):950. doi:10.1007/s12672-026-05054-5

Bergamaschi L, Indini A, Brecht IB, Almaraz RL, Reguerre Y, Eigentler TK, et al. European Standard Clinical Practice Recommendations for Cutaneous Melanoma in Children and Adolescents. Pediatric Blood & Cancer. n/a(n/a):e70244. doi:10.1002/1545-5017.70244

Bertocchini A, Crescentini L, Vinchesi E, Persano G, Madafferi S, Pardi V, et al. Laparoscopic Adrenal Compartment Resection for Paediatric Adrenal Neoplasms: Surgical Technique and Single-Centre Experience. European Journal of Haematology. n/a(n/a). doi:10.1111/ejh.70158

Buconi I, Zarfati A, Martucci C, Persano G, Natali GL, Brunetti G, et al. Pediatric Pleuropulmonary Blastoma Revealed By Massive Hemothorax: Multidisciplinary Diagnostic and Therapeutic Challenges. Journal of Pediatric Hematology/Oncology. 2026 Jul;48(5):e212. doi:10.1097/MPH.0000000000003204

Cakmakci S, Erturk A, Karakus E, Kiran MM, Erdem AY, Ozyoruk D, et al. Clinical Characteristics and Treatment Outcomes of Pediatric Pancreatic Solid Pseudopapillary Tumors: A Single-Center Experience. Turkish Archives of Pediatrics. 2026 Mar 4;61(3):246–53. doi:10.65717/TurkArchPediatr.2026.25324

Cavalheiro S, Pavon LF, de Farias CB, Nascimento FB, Lichtenfels M, Rodrigues JB, et al. Prediction of personalized therapeutic response in pediatric clivus chordoma: chemoresistance test. J Cancer Res Clin Oncol. 2026 May 26. doi:10.1007/s00432-026-06506-9

Guerra AD, Evageliou NF, Batra V, Dalton KL, Ortel S, Ashraf U, et al. A High-Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK-Rearranged Non–Small Cell Lung Cancer. Pediatric Blood & Cancer. 2026;73(7):e70322. doi:10.1002/1545-5017.70322

Imran R, Baha-Ul-Haq G, Tarar MD, Ahmad I, Tariq R. NUT carcinoma of the cheek managed with chemotherapy and surgical resection. BMJ Case Reports CP. 2026 Jan 1;19(1):e269655. doi:10.1136/bcr-2025-269655 PubMed PMID: 41592880.

Kuhlen M, Roganivic J, Naviglio S, Baecklund F, Bello R, Ben-Ami T, et al. Who leads, who treats, what dose? European paediatric differentiated thyroid carcinoma practice—an European Cooperative Study Group for Paediatric Rare Tumours survey. Eur J Endocrinol. 2026 Jun 1;194(6):756–68. doi:10.1093/ejendo/lvag091

Kurobe M, Ohashi S, Shibasaki T, Ohtsuka T, Maeda M, Kamio T, et al. Atypical pulmonary carcinoid in a pediatric patient requiring total pneumonectomy: A case report. Pediatrics International. 2026;68(1):e70361. doi:10.1111/ped.70361

Makowska A, Kontny U. Natural Killer (NK) Cells in Tumor Immunity: Limitations and Therapeutic Potential with a Focus on Nasopharyngeal Carcinoma and Comparison with T-Cell-Based Therapies. Cells. 2026 Jan;15(10):913. doi:10.3390/cells15100913

Mascarenhas L, Balzer B, Nguyen AT, Schwab JH. Contemporary Management of Standard Chordoma Arising in the Mobile Spine and Sacrum. JAAOS – Journal of the American Academy of Orthopaedic Surgeons. 2026 Mar 15;34(6):e832. doi:10.5435/JAAOS-D-24-01119

Okiro P, Hendricks M, Pillay K. Sex Cord-Stromal Tumours in Children: A Case Series. Pediatr Dev Pathol. 2026 May 1;29(3):200–9. doi:10.1177/10935266251414780

Riedmeier M, Frey H, Antonini SR, Canali GFL, Classen CF, Domínguez-Pinilla N, et al. Mitotane dosage, plasma levels, and anthropometric measurements in pediatric adrenocortical carcinoma. Endocrine Oncology. 2026 Jan 1;6(1). doi:10.1530/EO-24-0081

Rossi S, Barresi S, Giovannoni I, Genovese S, Costabile V, Stracuzzi A, et al. Melanomas and Mesenchymal Tumors Arising in Giant Congenital Melanocytic Nevi: Clinico-Pathological and Molecular Characterization of a Case Series. Pigment Cell & Melanoma Research. 2026;39(1):e70071. doi:10.1111/pcmr.70071

Sainulabdin G, Krishnan VP, Bhaskaran S, Krishnan Y. Adult-type epithelial neoplasms in children and adolescents—A retrospective analysis on a subgroup of very rare tumors. Indian Journal of Cancer. 2025 Dec;62(4):528. doi:10.4103/ijc.ijc_96_25

Silva D, Lopes-Pinto M, Ribeiro S, Barbosa D, Vasconcelos N, Marão R, et al. Pediatric papillary thyroid carcinoma: postoperative management and 14-year experience with radioiodine therapy at a Portuguese oncology centre. Eur J Pediatr. 2026 Apr 6;185(5):239. doi:10.1007/s00431-026-06894-7

Swart CC, de Krijger RR. Histopathological and Molecular Characteristics of Pediatric Adrenocortical Tumors: where Do we Stand? Endocr Pathol. 2026 Feb 19;37(1):9. doi:10.1007/s12022-026-09905-3

Taiwo OO, Angelini P, Awadh I, Domecq C, Foulkes WD, Mugalaasi H, et al. The SINEs were there: identification of a pathogenic Alu insertion in a patient with DICER1-related tumour predisposition. Journal of Medical Genetics. 2026 Jul 1;63(7):421–6. doi:10.1136/jmg-2025-111365 PubMed PMID: 41916722.

Virgone C, Redlich A. European Consensus Recommendations for Pediatric Neuroendocrine Tumor of the Appendix. Journal of the American College of Surgeons. 2026 Mar;242(3):739. doi:10.1097/XCS.0000000000001718

Zelenova E, Belysheva T, Orlova K, Grigorenko V, Semenova V, Sharapova E, et al. Squamous Cell Carcinoma of the Skin in a Teenager with Fanconi Anemia: A Challenging Treatment. International Journal of Molecular Sciences. 2026 Jan;27(10):4366. doi:10.3390/ijms27104366

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents – Kuhlen – Pediatric Blood & Cancer – Wiley Online Library [Internet]. [cited 2026 Jul 2]. Available from: https://onlinelibrary.wiley.com/doi/10.1002/1545-5017.70194

Low-Grade Mucoepidermoid Carcinoma Mimicking a Mucocele in the Soft Palate: A Case Report | Cureus [Internet]. [cited 2026 Jul 2]. Available from: https://www.cureus.com/articles/464807-low-grade-mucoepidermoid-carcinoma-mimicking-a-mucocele-in-the-soft-palate-a-case-report#!/

Redirecting [Internet]. [cited 2026 Jul 2]. Available from: https://www.google.com/url?q=https://doi.org/10.1002/1545-5017.70210&sa=D&source=docs&ust=1783007404697671&usg=AOvVaw1I8eb9Ml8fUx58OMQcYu0P

Shared PRAME epitopes are T-cell targets in NUT carcinoma | Journal for ImmunoTherapy of Cancer [Internet]. [cited 2026 Jul 2]. Available from: https://jitc.bmj.com/content/14/2/e013539

2025

Acevedo A, Indelicato DJ, Brisson RJ, Collier III AB, Bradley JA, Mailhot Vega RB, et al. Proton Therapy for Locally Advanced Unresectable Ameloblastoma in a Child. Pediatric Blood & Cancer. 2025;72(7):e31773. https://doi.org/10.1002/pbc.31773.

Arakawa A, Sugiyama M, Uchida E, Miyazaki B, Tao K, Isobe K, et al. Successful Multidisciplinary Treatment of Tracheal Lymphoepithelial Carcinoma in an Adolescent Patient. Pediatric Blood & Cancer. 2025;72(6):e31662. https://doi.org/10.1002/pbc.31662.

Arnaboldi SMC, Gattuso G, Nicolosi ML, Molinari S, Bettini LR, Leva E, et al. Management of ovarian granulosa cell tumor in childhood: a case report and recommendations for a multidisciplinary approach. Front Oncol. 2025 Nov 24;15. https://doi.org/10.3389/fonc.2025.1634166.

Ashayeri N, Khani P, Miri-Aliabad G, Jafari M, Pajouhi A. Malignant melanoma with bone metastases in a child: a case report and review of literature. Annals of Medicine and Surgery. 2025 Jan;87(1):318. https://doi.org/10.1097/ms9.0000000000002767.

Augustin EM, Indelicato DJ, Bradley JA, Fortune IV EC, Dagan R, Morris CG, et al. Long-Term Outcomes Following Radiotherapy for Pediatric Salivary Gland Tumors. Pediatric Blood & Cancer. 2025;72(5):e31571. https://doi.org/10.1002/pbc.31571.

Beckhorn CB, Rhodin KE, Leraas HJ, Farrow NE, Lee JS, Beasley GM, et al. National Trends in Management of the Nodal Basin for Pediatric Patients With Occult Stage III Melanoma in the United States. Pediatric Blood & Cancer. 2025;72(5):e31627. https://doi.org/10.1002/pbc.31627.

Bleyer A, Ries LAG, Cameron DB, Mansfield SA, Siegel SE, Barr RD. Colon, colorectal, and all cancer incidence increase in the young due to appendix reclassification. J Natl Cancer Inst. 2025 Jul 1;117(7):1340–9. https://doi.org/10.1093/jnci/djaf038.

Brisset C, Roumy M, Lacour B, Hescot S, Bras ML, Dijoud F, et al. Bronchial Carcinoid Tumors in Children and Adolescents. Pediatric Blood & Cancer. 2025;72(8):e31822. https://doi.org/10.1002/pbc.31822.

Chiaravalli S, Indini A, Del Vecchio M, Casanova M, Massimino M, Bergamaschi L, et al. Dabrafenib and Trametinib for the Treatment of Pediatric and Adolescent Melanoma: Single Center Experience Data From Italian Compassionate Use. Pediatric Blood & Cancer. 2025;72(5):e31644. https://doi.org/10.1002/pbc.31644.

Dholaria H, Tsetlina V, Simpson SK, Gillies E, Eswaran N, Rodriguez-Galindo C, et al. One-Two Punch: Combining Chemotherapy and Immunotherapy to Decrease Radiation Dose and Related Toxicity in Children and Adolescents with Nasopharyngeal Carcinoma. Clin Cancer Res. 2025 Aug 1;31(15):3124–32. https://doi.org/10.1158/1078-0432.ccr-24-3546.

Faure-Conter C, Rome A, Orbach D, You B, Bolze PA. Gestational trophoblastic diseases and neonatal choriocarcinoma. Bulletin du Cancer. 2026 Feb 1;113(2):273–8. https://doi.org/10.1016/j.bulcan.2025.10.007.

Fincke VE, Sax I, Kunstreich M, Golas MM, Hofmann TG, Schlesner M, et al. Double heterozygous pathogenic variants in BRCA2 and CHEK2 in a girl with adrenocortical carcinoma. Explor Endocr Metab Dis. 2025 Apr 17;2:101429. https://doi.org/10.37349/eemd.2025.101429.

Gaze MN, Handkiewicz-Junak D, Hladun R, Laetsch TW, Sorge C, Sparks R, et al. Safety and dosimetry of [177Lu]Lu-DOTA-TATE in adolescent patients with somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumours, or pheochromocytomas and paragangliomas: Primary analysis of the Phase II NETTER-P study. Eur J Nucl Med Mol Imaging. 2025 Sep 1;52(11):4001–15. https://doi.org/10.1007/s00259-025-07246-7.

Godard F, Haffreingue A, Hameury F, Sarnacki S, Hervieux E, Bonnard A, et al. Pulmonary Consequences of Surgical Treatment in Children’s Primary Lung Tumors: A National Retrospective Study. Pediatric Blood & Cancer. 2025;72(3):e31522. https://doi.org/10.1002/pbc.31522.

Guo K, Yang L, Huang Z, Qian K, Shi Y, Fei M, et al. Single-Cell RNA Sequencing Reveals the Heterogeneity in Differentiation Trajectory and Tumor Microenvironment Leading to More Aggressive Phenotypes of Papillary Thyroid Cancer in Children and Young Adult Patients. Advanced Science. 2025;12(39):e17672. https://doi.org/10.1002/advs.202417672.

Halalsheh H, Barbar M, AlAdwan M, Sultan I. Pediatric Gastric and Colorectal Cancers: Insights From a 16-Year Single-Center Experience. Pediatric Blood & Cancer. 2025;72(9):e31860. https://doi.org/10.1002/pbc.31860.

Harris AK, Nelson AT, Watson D, Mallinger PHR, Messinger YH, Frazier AL, et al. Ovarian juvenile granulosa cell tumor: A report from the International Ovarian and Testicular Stromal Tumor and International Pleuropulmonary Blastoma/DICER1 Registries. Cancer. 2025;131(9):e35862. https://doi.org/10.1002/cncr.35862.

Hirano T, Hoshi R, Yamaoka B, Ono K, Watanabe Y, Goto S, et al. Pediatric Alpha-Fetoprotein-Producing Gastric Cancer Presenting With Dysphagia and Multiple Liver Tumors. Cancer Reports. 2025;8(9):e70348. https://doi.org/10.1002/cnr2.70348.

Jansen FA, Bakhuizen J, Kester L, de Krijger RR. DICER1 Syndrome: What Do We Know of the Pathogenetic Mechanisms? Cancers. 2025 Jan;17(17):2885. https://doi.org/10.3390/cancers17172885.

Jiar ME, Huybrechts S, Pissaloux D, Tirode F, Pouget C, Sales F, et al. Childhood melanoma ex-blue naevus leading to the identification of a BAP1 tumour predisposition syndrome. Pathology. 2025 Oct 1;57(6):797–9. https://doi.org/10.1016/j.pathol.2025.05.004.

Karges K, Kunstreich M, Abele M, Fuchs J, Vokuhl C, Brecht IB, et al. Gastrointestinal Neuroendocrine Neoplasms in Children and Adolescents: Data from the German MET Studies (1997–2024). Neuroendocrinology. 2025 Sep 25;116(1):43–54. https://doi.org/10.1159/000548618.

Karges K, Kunstreich M, Pape UF, Fuchs J, Vokuhl C, Abele M, et al. Pancreatic neuroendocrine tumors in children and adolescents—Data from the German MET studies (1997–2023). Journal of Neuroendocrinology. 2025;37(8):e70039. https://doi.org/10.1111/jne.70039.

Kuhlen M, Karges K, Kunstreich M, Abele M, Fuchs J, Vokuhl C, et al. Invisible origins: paediatric neuroendocrine neoplasms of unknown primary site in the MET registry and SEER database. ESMO Rare Cancers. 2025 Dec 1;4. https://doi.org/10.1016/j.esmorc.2025.100026.

Kuhlen M, Kunstreich M, Dunstheimer D, Aumann N, Lorenz K, Luster M, et al. Autoimmune thyroiditis in paediatric thyroid cancer: clinical features and outcomes. Eur J Endocrinol. 2025 Jul 1;193(1):48–55.https://doi.org/10.1093/ejendo/lvaf133.

Kuhlen M, Kunstreich M, Eilsberger F, Luster M, Redlich A. Pediatric differentiated thyroid carcinoma leading to fatal lung fibrosis. European Thyroid Journal. 2025 Feb 1;14(1). https://doi.org/10.1530/ETJ-24-0341.

Kuhlen M, Kunstreich M, Eilsberger F, Lorenz K, Abele M, Brecht IB, et al. Risk-adapted therapy in pediatric thyroid cancer: initial experience from a national reference program by the MET group. European Thyroid Journal. 2025 Aug 1;14(4). https://doi.org/10.1530/ETJ-25-0035.

Kuhlen M, Virgone C, Rigaud C, Irtan S, Casey R, Pamporaki C, et al. European clinical guidance for the management of adrenal and extra-adrenal paraganglioma in children and adolescents: a consensus by the EXPeRT group. Eur J Endocrinol. 2025 Dec 1;193(6):G113–26. https://doi.org/10.1093/ejendo/lvaf239.

Kuhlen M, Wudy SA, Baumann C, Vokuhl C, Hartmann MF, Kunstreich M, et al. Prolonged symptom duration and the potential for gradual progression in pediatric adrenocortical tumors: observations from the MET studies. Journal of Pediatric Endocrinology and Metabolism. 2025 Sep 1;38(9):931–8. https://doi.org/10.1515/jpem-2025-0198.

Lemeshev MA, Andreeva NA, Druy AE, Sidorov IV, Konovalov DM, Tverdov IV, et al. A Unique Case of Recurrence After Adjuvant Chemotherapy in Pleuropulmonary Blastoma (PPB) Type I With Transformation to PPB Type III. Pediatric Blood & Cancer. 2025;72(5):e31642. https://doi.org/10.1002/pbc.31642.

Luckie T, Chelius D, Dimachkieh A, Quintanilla N, Roy A, Sher AC, et al. Response to neoadjuvant selpercatinib in a pediatric patient with advanced papillary thyroid carcinoma: a case report. Pediatric Hematology and Oncology. 2025 May 19;42(4):250–5. https://doi.org/10.1080/08880018.2025.2466022.

Mahajan P, May SB, Shekar M, Werny D, Patterson BC, Chan CM, et al. Multicenter Retrospective Analysis of Pediatric Differentiated Thyroid Carcinoma: Treatment Practices and Outcomes Prior to Pediatric American Thyroid Association Guidelines Implementation. Pediatric Blood & Cancer. 2025;72(4):e31545. https://doi.org/10.1002/pbc.31545.

McCarty KL, Watt T, Dan TD, Timmerman RD, Kumar KA. Use of PULSAR (personalized ultra-fractionated stereotactic adaptive radiotherapy) as consolidation with immune checkpoint inhibition in the treatment of pediatric metastatic melanoma. Radiat Oncol. 2025 Aug 21;20(1):132. https://doi.org/10.1186/s13014-025-02691-y.

Mehrhoff C, Dagalakis U, Bauer AJ, Mahajan P, Laetsch TW, Mostoufi-Moab S. Navigating Multidisciplinary Care in Pediatric Thyroid Carcinoma: Insights From Children’s Oncology Group Sites. Pediatric Blood & Cancer. 2025;72(10):e31919. https://doi.org/10.1002/pbc.31919.

Miele E, Rossi S, Stracuzzi A, Patrizi S, Barresi S, Cajozzo M, et al. Epigenomic characterization and therapeutic challenges of melanoma arising in giant nevi in pediatric patients. Discov Onc. 2025 Nov 25;16(1):2164. https://doi.org/10.1007/s12672-025-03965-3.

Mucha M, Bühner S, Loßner M, Fincke VE, Reitsam NG, Dorn F, et al. Multi-modal omics analysis of a paediatric melanoma highlights mechanisms underlying treatment resistance. Commun Med. 2025 Oct 30;5(1):448. https://doi.org/10.1038/s43856-025-01201-1.

Paul Boulanger K, McCuaig C, Roy AA, Kokta V, Prudhomme N, McMahon J, et al. Striking improvement with targeted therapy in an anaplastic lymphoma kinase-positive atypical giant congenital melanocytic naevus of the right lower limb: a case report. Br J Dermatol. 2025 Dec 1;193(6):1248–51. https://doi.org/10.1093/bjd/ljaf334.

Peet C, Elmaraghi C, Abdel-Aziz T, Liang HH, Gains JE, Nguyen T, et al. Molecular radiotherapy for adult type metastatic neuroendocrine tumours in children. Eur J Nucl Med Mol Imaging. 2025 Sep 1;52(11):4016–24. https://doi.org/10.1007/s00259-025-07247-6.

Pyrbot RD, Peters NJ, Kanojia RP, Chatterjee D, Singh J, Solanki S, et al. Bronchial Mucoepidermoid Carcinoma in a Child: A Case Report and Technical Considerations. Journal of Indian Association of Pediatric Surgeons. 2025 Dec;30(6):783. https://doi.org/10.4103/jiaps.jiaps_5_25.

Raikot SR, Potter DDJ, Day CN, Gudmundsdottir H, Allen-Rhoades WA, Habermann EB, et al. Appendectomy vs Right Hemicolectomy for Pediatric Neuroendocrine Tumor of the Appendix in a National Cohort: A Call to Further Decrease Colectomy. Journal of the American College of Surgeons. 2025 Oct;241(4):620. https://doi.org/10.1097/xcs.0000000000001435.

Redlich A, Pfaehler E, Kunstreich M, Schmutz M, Lapa C, Kuhlen M. Machine Learning Prediction of Recurrence in Pediatric Thyroid Cancer: Malignant Endocrine Tumors Cohort Analysis Using XGBoost and SHAP. J Clin Endocrinol Metab. 2026 Mar 1;111(3):e844–52. https://doi.org/10.1210/clinem/dgaf487.

Richard C, Carton M, Hazkani I, Couloigner V, Sheyn A, Rastatter J, et al. Cervical Lymph Node Invasion in Pediatric Salivary Gland Malignancies: Clinical Overview and Therapeutic Implications. Pediatric Blood & Cancer. 2025;72(4):e31581. https://doi.org/10.1002/pbc.31581.

Riedmeier M, Idkowiak J, Frey H, Antonini SRR, Canali GFL, Classen CF, et al. Inflammation-based score in pediatric adrenocortical carcinoma. Endocrine-Related Cancer. 2025 May 1;32(5). https://doi.org/10.1530/ERC-24-0244.

Riedmeier M, Schlötelburg W, Agarwal S, Biswas A, Ekinci S, Fassnacht M, et al. Multidisciplinary Tumor Board Evaluation of Pediatric Patients with Adrenocortical Tumors Across Seven International Centers. Cancers. 2025 Jan;17(6):1014. https://doi.org/10.3390/cancers17061014.

Schneider DT, Witowski A, Abele M, Benesch M, Bernbeck B, Blessing T, et al. Testicular and ovarian Juvenile granulosa cell tumors in children and adolescents: Analysis of 113 patients registered to the German Registry for Rare Pediatric Tumors (STEP). Cancer. 2025;131(9):e35861. https://doi.org/10.1002/cncr.35861.

Sharma D, Qureshi S, Khanna N, Manjali J, Laskar S, Baheti A, et al. Melanotic Neuroectodermal Tumor of Infancy: Clinicopathological Evaluation of a 10-Year Consecutive Case Series from a Tertiary Cancer Center. Head and Neck Pathol. 2025 Apr 25;19(1):47. https://doi.org/10.1007/s12105-025-01789-9.

Srivatsa S, Aldrink JH, Haque MR, Murphy A, Gehle D, Halepota H, et al. ASO Visual Abstract: Surgical Management and Outcomes in Pediatric Adrenocortical Carcinoma: A Pediatric Surgical Oncology Research Collaborative Study. Ann Surg Oncol. 2026 Mar 1;33(3):2753–4. https://doi.org/10.1245/s10434-025-18869-3.

Srivatsa S, Aldrink JH, Haque MR, Murphy A, Gehle D, Halepota H, et al. Surgical Management and Outcomes in Pediatric Adrenocortical Carcinoma: A Pediatric Surgical Oncology Research Collaborative Study. Ann Surg Oncol. 2026 Mar 1;33(3):2712–28. https://doi.org/10.1245/s10434-025-18731-6.

Sun NY, Kumar S, Kim YS, Varghese D, Mendoza A, Nguyen R, et al. Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma. Nat Commun. 2025 Jul 1;16(1):5511. https://doi.org/10.1038/s41467-025-60649-w.

Tejza B, Hetman M, Węcławek-Tompol J, Kałwak K, Rutynowska O, Dembowska-Bagińska B, et al. Pleuropulmonary Blastoma in Children: A Nationwide Multicenter Study. Cancers. 2025 Jan;17(19):3223. doi:10.3390/cancers17193223

Tuli G, Munarin J, Vallero SG, Piglione M, Biasin E, De Sanctis L, et al. Mitotane-Induced Endocrine Alterations in Children with Adrenocortical Carcinoma: Clinical Implications from a 20-Year Retrospective Study. Children. 2025 Aug;12(8):1031. doi:10.3390/children12081031

Tüller P, Kiefer T, Jabbarli L, Papaioannou K, Schramm K, Barwinski N, et al. Melanoma of the Choroid and Ciliary Body in Children: Remission of Metastatic Melanoma of the Choroid After Treatment With Chemotherapy and Immune Checkpoint Inhibition. Pediatric Blood & Cancer. 2026;73(2):e32147. doi:10.1002/pbc.32147

Virgone C, Roganovic J, Rindi G, Kuhlen M, Jamsek J, Panagopoulou P, et al. Appendiceal neuroendocrine tumors in children and adolescents: The European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT) diagnostic and therapeutic recommendations. Surgery. 2025 Aug;184:109451. doi:10.1016/j.surg.2025.109451 PubMed PMID: 40450811.

Wasserman JD, Schneider KW, Achatz MI, Nakano Y, Zelley K, Gallinger B, et al. Updated Recommendations for Pediatric Surveillance in Hereditary Endocrine Neoplasia Syndromes: Multiple Endocrine Neoplasias, Hyperparathyroidism–Jaw Tumor Syndrome, and Carney Complex. Clin Cancer Res. 2025 Sep 2;31(17):3628–37. doi:10.1158/1078-0432.CCR-24-3860

Weihrauch-Blüher S, Bernig T, Kaiser M, Schneider D, Kunze C, Ronstedt K, et al. Hormone-active ovarian steroid cell tumor in a 2-year-old girl. Journal of Pediatric Endocrinology and Metabolism. 2025 Oct 1;38(10):1092–7. doi:10.1515/jpem-2025-0271

Wild H, Liebmann A, Maennel L, Maschke L, Block A, Kager L, et al. Colorectal Carcinoma in Childhood and Adolescence: Microsatellite Instability Correlates With a Favorable Prognosis. Pediatric Blood & Cancer. 2025;72(8):e31830. doi:10.1002/pbc.31830

Yang AT, Lai S ting T, Laetsch TW, Bhatti T, Baloch Z, Surrey LF, et al. Molecular Landscape and Therapeutic Strategies in Pediatric Differentiated Thyroid Carcinoma. Endocr Rev. 2025 Jun 1;46(3):397–417. doi:10.1210/endrev/bnaf003

You Y, Lu S, Sun F, He X, Wang J, Huang J, et al. Pediatric NUT carcinoma: a patient series and literature review. BMC Pediatr. 2025 Oct 31;25(1):889. doi:10.1186/s12887-025-06278-0

2024

Busico A, Gasparini P, Rausa E, Cattaneo L, Bozzi F, Silvestri M, et al. Molecular profiling of pediatric and young adult colorectal cancer reveals a distinct genomic landscapes and potential therapeutic avenues. Sci Rep. 2024 Jun 7;14(1):13138. https://doi.org/10.1038/s41598-024-64149-7.

Carli D, Rondot F, Luca M, Campello A, Vallero SG, Tirtei E, et al. Molecular and Clinical Features of Adrenocortical Tumors in Beckwith–Wiedemann Spectrum. Cancers. 2024 Jan;16(23):3967. https://doi.org/10.3390/cancers16233967.

Carlo DD, Fichera G, Dumont B, Pozzo E, Timmermann B, Luscan R, et al. Olfactory neuroblastoma in children and adolescents: The EXPeRT recommendations for diagnosis and management. EJC Paediatric Oncology. 2024 Jun 1;3. https://doi.org/10.1016/j.ejcped.2023.100136.

Casey RT, Hendriks E, Deal C, Waguespack SG, Wiegering V, Redlich A, et al. International consensus statement on the diagnosis and management of phaeochromocytoma and paraganglioma in children and adolescents. Nat Rev Endocrinol. 2024 Dec;20(12):729–48. https://doi.org/10.1038/s41574-024-01024-5.

Castex MP, Stefanowicz J, Clement L, Węcławek-Tompol J, Hameury F, Fresneau B, et al. Choriocarcinoma in neonates and infants: A severe but curable disease. Pediatric Blood & Cancer. 2024;71(8):e31124. https://doi.org/10.1002/pbc.31124.

Chen W, Bai J, Fang Y, Wu D, Zhang B. Prognostic factors and surgical management in pediatric primary lung cancer: a retrospective cohort study using SEER data. Translational Pediatrics. 2024 Oct 31;13(10):1671683–1671683. https://doi.org/10.21037/tp-24-174.

Courtel T, Orbach D, Lacour B, Roumy M, Hescot S, Desandes E, et al. Childhood pancreatic neuroendocrine neoplasms: A national experience. Pediatric Blood & Cancer. 2025;72(2):e31258. https://doi.org/10.1002/pbc.31258.

de Bresser CJM, de Krijger RR. The Molecular Classification of Pheochromocytomas and Paragangliomas: Discovering the Genomic and Immune Landscape of Metastatic Disease. Endocr Pathol. 2024 Dec 1;35(4):279–92. https://doi.org/10.1007/s12022-024-09830-3.

De Leonardis F, Greco Miani V, Vallese S, Barresi S, Marulli G, Novielli C, et al. A Novel NUTM1-NSMCE2 Fusion Gene in a Pediatric Chest NUT Carcinoma. Journal of Pediatric Hematology/Oncology. 2024 Jul;46(5):e322. https://doi.org/10.1097/mph.0000000000002884.

Forchhammer S, Aebischer V, Lenders D, Seitz CM, Schroeder C, Liebmann A, et al. Characterization of PRAME immunohistochemistry reveals lower expression in pediatric melanoma compared to adult melanoma. Pigment Cell & Melanoma Research. 2024;37(4):453–61. https://doi.org/10.1111/pcmr.13167.

Forchhammer S, Pop OT, Hahn M, Aebischer V, Seitz CM, Schroeder C, et al. Expression of the tumor antigens NY-ESO-1, tyrosinase, MAGE-A3, and TPTE in pediatric and adult melanoma: a retrospective case control study. Virchows Arch. 2024 Aug 1;485(2):335–46. https://doi.org/10.1007/s00428-024-03846-0.

Handkiewicz-Junak D, Niedziela M, Lewiński A, Bossowski A, Chmielik E, Czarniecka A, et al. Diagnostics and treatment of differentiated thyroid carcinoma in children — Guidelines of the Polish National Scientific Societies, 2024 Update. Endokrynologia Polska. 2024;75(6):565–91. https://doi.org/10.5603/ep.103845.

Klijanienko J, Gauthier A, Brisse HJ, Pierron G, Orbach D. Parotid Keratocystoma: Fine Needle Aspiration Cytomorphology With Ancillary Testing Results. Diagnostic Cytopathology. 2025;53(4):E61–5. https://doi.org/10.1002/dc.25438.

Kuhlen M, Kunstreich M, Pape UF, Seitz G, Lessel L, Vokuhl C, et al. Lymph node metastases are more frequent in paediatric appendiceal NET ≥1.5 cm but without impact on outcome – Data from the German MET studies. European Journal of Surgical Oncology. 2024 Apr 1;50(4). https://doi.org/10.1016/j.ejso.2024.108051.

Mansfield SA, De Corti F, Aldrink JH, Pire A, Crocoli A, Dall’Igna P, et al. Rare tumors II: Adrenocortical tumors, neuroendocrine tumors of the appendix, pheochromocytoma and paraganglioma, pancreatoblastoma and solid pseudopapillary tumors of the pancreas. Pediatric Blood & Cancer. 2025;72(S2):e31207. https://doi.org/10.1002/pbc.31207.

Marjańska A, Pawińska-Wąsikowska K, Wieczorek A, Drogosiewicz M, Dembowska-Bagińska B, Bobeff K, et al. Anti-PD-1 Therapy in Advanced Pediatric Malignancies in Nationwide Study: Good Outcome in Skin Melanoma and Hodgkin Lymphoma. Cancers. 2024 Jan;16(5):968. https://doi.org/10.3390/cancers16050968.

Min V, Corradini N, Macagno N, Orbach D, Reguerre Y, Petit P, et al. Gastrointestinal stromal tumours (GIST) in children: An update of this orphan disease. Bulletin du Cancer. 2025 Mar 1;112(3):348–57. https://doi.org/10.1016/j.bulcan.2024.07.011.

Neirotti A, Barat V, Coppo P, La Selva R, Manicone R, Cotti R, et al. Therapy with sirolimus in vascular anomalies: the experience of two Italian centers on 14 pediatric patients. Front Pediatr. 2024 Jul 17;12. https://doi.org/10.3389/fped.2024.1434493.

O’Neill AF, Ribeiro RC, Pinto EM, Clay MR, Zambetti GP, Orr BA, et al. Pediatric Adrenocortical Carcinoma: The Nuts and Bolts of Diagnosis and Treatment and Avenues for Future Discovery. CMAR. 2024 Sep 7;16:1141–53. https://doi.org/10.2147/cmar.s348725.

Raemy A, May L, Sala N, Diezi M, Beck-Popovic M, Broome M. Anti-MAPK Targeted Therapy for Ameloblastoma: Case Report with a Systematic Review. Cancers. 2024 Jan;16(12):2174. https://doi.org/10.3390/cancers16122174.

Réti Z, Tabák ÁGy, Garami M, Kalina I, Kiss G, Sápi Z, et al. Spontaneous and Treatment-Related Changes of Serum Calcitonin in Medullary Thyroid Cancer: Long-Term Experience in a Patient With Multiple Endocrine Neoplasia Type 2B. JCO Precis Oncol. 2024 May;(8):e2300675. https://doi.org/10.1200/po.23.00675.

Roganovic J, Virgone C, Ben-Ami T, Reguerre Y, Ferrari A, Orbach D, et al. Paediatric very rare tumours registration and management in European countries with low health expenditure average rates. Clin Transl Oncol. 2025 Apr 1;27(4):1779–88. https://doi.org/10.1007/s12094-024-03674-3.

Sargen MR, Barnhill RL, Elder DE, Swetter SM, Prieto VG, Ko JS, et al. Evaluation and Surgical Management of Pediatric Cutaneous Melanoma and Atypical Spitz and Non-Spitz Melanocytic Tumors (Melanocytomas): A Report From Children’s Oncology Group. J Clin Oncol. 2025 Mar 20;43(9):1157–67. https://doi.org/10.1200/JCO.24.01154.

Schneider DT, Ferrari A, Orbach D, Virgone C, Reguerre Y, Godzinski J, et al. A virtual consultation system for very rare tumors in children and adolescents – an initiative of the European Cooperative Study Group in Rare Tumors in Children (EXPeRT). EJC Paediatric Oncology. 2024 Jun 1;3. https://doi.org/10.1016/j.ejcped.2023.100137.

Schultz KAP, Nelson AT, Mallinger PHR, Harris AK, Kamihara J, Baldinger S, et al. DICER1-Related Tumor Predisposition: Identification of At-risk Individuals and Recommended Surveillance Strategies. Clin Cancer Res. 2024 Dec 16;30(24):5681–92. https://doi.org/10.1158/1078-0432.CCR-24-1532.

Stetson A, Saluja S, Cameron DB, Mansfield SA, Polites SF, Honeyman JN, et al. Surgical management of rare tumors (Part 1). Pediatric Blood & Cancer. 2025;72(S2):e31287. https://doi.org/10.1002/pbc.31287.

Veronez LC, Xavier AET, Nagano LF, Correa CAP, Borges KS, Santos P, et al. Identifying prognostic hub genes and key pathways in pediatric adrenocortical tumors through RNA sequencing and Co-expression analysis. Molecular and Cellular Endocrinology. 2024 Dec 1;594:112383. https://doi.org/10.1016/j.mce.2024.112383.

Xavier AET, Veronez LC, Nagano LFP, Correa CAP, Baroni M, Ramos MS, et al. Low PRKAB2 Expression Is Associated with Poor Outcomes in Pediatric Adrenocortical Tumors, and Treatment with Rottlerin Increases the PRKAB2 Level and Inhibits Tumorigenic Aspects in the NCI-H295R Adrenocortical Cancer Cell Line. Cancers. 2024 Jan;16(6):1094. https://doi.org/10.3390/cancers16061094.

Yildiz G, Torun Bayram M, Ünlü ŞM, Soylu A, Kavukçu S, Olgun N. Nivolumab-associated IgA Nephropathy in a Child With Malignant Melanoma. Journal of Pediatric Hematology/Oncology. 2024 Oct;46(7):e534. https://doi.org/10.1097/mph.0000000000002931.

2023

Krawczyk M, Styczewska M, Fernandez C, Alaggio R, Szydlowski J, Brecht I, et al. Focus on melanotic neuroectodermal tumor of infancy. EJC Paediatric Oncology, Volume 3, 2023, 100141. https://doi.org/10.1016/j.ejcped.2023.100141.

Orbach D, Brecht I, Corradini N, Bouchoucha Y, Roganovic J, Bourdeaut F, et al. The role of cancer predisposition syndrome in children and adolescents with very rare tumours. EJC Paediatric Oncology, Volume 2, 2023, 100023. https://doi.org/10.1016/j.ejcped.2023.100023.

Roganovic J, Bien E, Ferrari A, Vassal G, Trama A, Casali PG, et al. Solutions for optimal care and research for children and adolescents with extremely rare cancers developed within the Joint Action for Rare Cancers (JARC). EJC Paediatric Oncology, Volume 2, 2023, 100130. https://doi.org/10.1016/j.ejcped.2023.100130.

Schneider DT, Orbach D, Virgone C, Reguerre Y, Godzinski J, Bien E, et al. Salivary Gland Carcinomas in Children and Adolescents: A Retrospective Analysis of the European Cooperative Study Group for Pediatric Rare Tumours (EXPeRT). EJC Paediatric Oncology, Volume 2, 2023, 100129, https://doi.org/10.1016/j.ejcped.2023.100129.

Virgone C, Ben Ami T, Roganovic J, Bien E, Reguerre Y, Ferrari A, et al. Age-related biological differences in children’s and adolescents’ very rare tumors. EJC Paediatric Oncology, Volume 2, 2023, 100027, https://doi.org/10.1016/j.ejcped.2023.100027.

Lemelle L, Flaadt T, Fresneau B, Moya-Plana A, Timmermann B, Roganovic J, et al. NUT Carcinoma in Children and Adolescents: The Expert European Standard Clinical Practice Harmonized Recommendations. J Pediatr Hematol Oncol. 2023 May 1;45(4):165-173. https://doi.org/10.1097/mph.0000000000002568.

2022

Abele M, Bajčiová V, Wright F, Behjati S, Voggel S, Schneider DT, et al. Primary lung carcinoma in children and adolescents: An analysis of the European Cooperative Study Group on Paediatric Rare Tumours (EXPeRT). Eur J Cancer. 2022 Nov;175:19-30. https://doi.org/10.1016/j.ejca.2022.08.007.

2021

Ben-Ami T, Kontny U, Surun A, Brecht IB, Almaraz RL, Dragomir M, et al. Nasopharyngeal carcinoma in children and adolescents: The EXPeRT/PARTNER diagnostic and therapeutic recommendations. Pediatr Blood Cancer. 2021 Jun;68 Suppl 4:e29018. https://doi.org/10.1002/pbc.29018.

Bien E, Roganovic J, Krawczyk MA, Godzinski J, Orbach D, Cecchetto G, Barthlen W, et al. Pancreatoblastoma in children: EXPeRT/PARTNER diagnostic and therapeutic recommendations. Pediatr Blood Cancer. 2021 Jun;68 Suppl 4:e29112. https://doi.org/10.1002/pbc.29112.

Bisogno G, Sarnacki S, Stachowicz-Stencel T, Minard Colin V, Ferrari A, Godzinski J, et al. Pleuropulmonary blastoma in children and adolescents: The EXPeRT/PARTNER diagnostic and therapeutic recommendations. Pediatr Blood Cancer. 2021 Jun;68 Suppl 4(Suppl 4):e29045. https://doi.org/10.1002/pbc.29045.

Ferrari A, Lopez Almaraz R, Reguerre Y, Cesen M, Bergamaschi L, Indini A, et al. Cutaneous melanoma in children and adolescents: The EXPeRT/PARTNER diagnostic and therapeutic recommendations. Pediatr Blood Cancer. 2021 Jun;68 Suppl 4:e28992. https://doi.org/10.1002/pbc.28992.

Schneider DT, Orbach D, Ben-Ami T, Bien E, Bisogno G, Brecht IB, et al. Consensus recommendations from the EXPeRT/PARTNER groups for the diagnosis and therapy of sex cord stromal tumors in children and adolescents. Pediatr Blood Cancer. 2021 Jun;68 Suppl 4:e29017. https://doi.org/10.1002/pbc.29017.

Surun A, Schneider DT, Ferrari A, Stachowicz-Stencel T, Rascon J, Synakiewicz A, et al. Salivary gland carcinoma in children and adolescents: The EXPeRT/PARTNER diagnosis and treatment recommendations. Pediatr Blood Cancer. 2021 Jun;68 Suppl 4:e29058. https://doi.org/10.1002/pbc.29058.

Virgone C, Roganovic J, Vorwerk P, Redlich A, Schneider DT, Janic D, et al. Adrenocortical tumours in children and adolescents: The EXPeRT/PARTNER diagnostic and therapeutic recommendations. Pediatr Blood Cancer. 2021 Jun;68 Suppl 4:e29025. https://doi.org/10.1002/pbc.29025.

2020

Orbach D, André N, Brecht IB, López Almaraz R, Ben-Ami T, Vermersch S, et al. Mesothelioma in children and adolescents: the European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT) contribution. Eur J Cancer. 2020 Nov;140:63-70. https://doi.org/10.1016/j.ejca.2020.09.011.

2019

Ferrari A, Schneider DT, Bisogno G, Trama A. Joining forces for pediatric very rare tumors. Oncotarget. 2019 May 3;10(33):3084-3085. https://doi.org/10.18632/oncotarget.26871.

Ferrari A, Brecht IB, Gatta G, Schneider DT, Orbach D, Cecchetto G, et al. Defining and listing very rare cancers of paediatric age: consensus of the Joint Action on Rare Cancers in cooperation with the European Cooperative Study Group for Pediatric Rare Tumors. Eur J Cancer. 2019 Mar;110:120-126. https://doi.org/10.1016/j.ejca.2018.12.031.

2018

Brecht IB, De Paoli A, Bisogno G, Orbach D, Schneider DT, Leiter U, et al. Pediatric patients with cutaneous melanoma: A European study. Pediatr Blood Cancer. 2018 Jun;65(6):e26974. https://doi.org/10.1002/pbc.26974.

2017

Cecchetto G, Ganarin A, Bien E, Vorwerk P, Bisogno G, Godzinski J, et al. Outcome and prognostic factors in high-risk childhood adrenocortical carcinomas: A report from the European Cooperative Study Group on Pediatric Rare Tumors (EXPeRT). Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26368. https://doi.org/10.1002/pbc.26368.

2015

Stachowicz-Stencel T, Orbach D, Brecht I, Schneider D, Bien E, Synakiewicz A, et al. Thymoma and thymic carcinoma in children and adolescents: a report from the European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT). Eur J Cancer. 2015 Nov;51(16):2444-52. https://doi.org/10.1016/j.ejca.2015.06.121.

Schneider DT, Orbach D, Cecchetto G, Stachowicz-Stencel T, Brummel B, Brecht IB, et al. Ovarian Sertoli Leydig cell tumours in children and adolescents: an analysis of the European Cooperative Study Group on Pediatric Rare Tumors (EXPeRT). Eur J Cancer. 2015 Mar;51(4):543-550. https://doi.org/10.1016/j.ejca.2014.11.013.

2012

Bisogno G, Ferrari A, Bien E, Brecht IB, Brennan B, Cecchetto G, et al. Rare cancers in children – The EXPeRT Initiative: a report from the European Cooperative Study Group on Pediatric Rare Tumors. Klin Padiatr. 2012 Oct;224(6):416-20. https://doi.org/10.1055/s-0032-1327608.

2011

Bien E, Godzinski J, Dall’igna P, Defachelles AS, Stachowicz-Stencel T, Orbach D, et al. Pancreatoblastoma: a report from the European cooperative study group for paediatric rare tumours (EXPeRT). Eur J Cancer. 2011 Oct;47(15):2347-52. https://doi.org/10.1016/j.ejca.2011.05.022.